Capsule Filling Machine
Capsule Filling Machine
What Is Capsule Filling Machine
A capsule filling machine is an automated pharmaceutical equipment used to fill empty hard gelatin or HPMC capsules with a precisely measured dose of powder, granules, pellets, or liquid formulations. It automates the complete encapsulation process, separating the capsule cap and body, dispensing the formulation, rejoining, and ejecting the finished capsule, ensuring consistent dosing accuracy, hygiene, and high throughput across every batch.
Unlike manual filling methods, a capsule filling machine operates within a fully enclosed, parameter-controlled environment, reducing operator dependency, minimising cross-contamination risk, and delivering repeatable results at any production scale. Equipped with PLC controls, SCADA data logging, and compliance features such as 21 CFR Part 11 and GAMP5, it is essential equipment for cGMP-compliant oral solid dosage manufacturing.
Encapsulation systems engineered for every scale and application.
Seven capsule filling equipment configurations designed to handle R&D, standard production, high-speed, and high-containment requirements, with precise control over dosing, capsule handling, and process parameters at every stage.
R&D Model
The F Plus R&D Model Capsule Filling Machine is purpose-built for research, development, and small-batch encapsulation trials, enabling formulation scientists to develop, test, and optimise capsule formulations before scaling to commercial production. Compact in footprint yet precise in performance, it supports multiple capsule sizes and fill types, including powders, granules, and pellets, within a controlled, cGMP-compatible environment. Designed to minimise material consumption while delivering accurate and reproducible fill weights, it is the ideal starting point for new formulation development and process validation activities.
Semiautomatic Series
The F Plus Semiautomatic Capsule Filling Machine Series bridges the gap between manual filling and full automation, offering a reliable and flexible solution for small to medium-scale production environments. Combining operator-assisted capsule loading with automated dosing, closing, and ejection functions, it significantly reduces manual effort while maintaining process consistency and fill weight accuracy. Built from pharmaceutical-grade stainless steel and designed for easy cleaning and changeover, the Semiautomatic Series is well-suited for contract manufacturers, multi-product facilities, and operations scaling up from R&D to commercial batch sizes.
PF Series
The F Plus PF Series is a fully automatic capsule filling platform engineered for reliable, mid-to-high speed production across a wide range of capsule sizes and formulation types. Featuring precision dosing mechanisms, automated capsule orientation and separation, and real-time process monitoring, the PF Series delivers consistent fill weight accuracy and high output with minimal operator intervention. With its robust mechanical design, quick-change format parts, and PLC-based control system, it is built for pharmaceutical and nutraceutical manufacturers seeking dependable, scalable, and cGMP-compliant encapsulation performance.
XTR Series
The F Plus XTR Series represents the high-speed tier of the F Plus capsule filling range, designed for large-scale pharmaceutical manufacturing operations where output, precision, and uptime are critical. Engineered for continuous, high-throughput production, the XTR Series incorporates advanced dosing technology, intelligent weight control, and automated process management to deliver superior fill accuracy across every capsule and every batch. With 21 CFR Part 11 and GAMP5-compliant controls, SCADA integration, and minimal downtime changeover capability, the XTR Series is built to meet the demands of high-volume commercial-scale encapsulation.
Containment Series
The F Plus Containment Series Capsule Filling Machine is engineered for encapsulation applications that demand the highest levels of operator and environmental protection, particularly for potent, cytotoxic, or highly sensitising active pharmaceutical ingredients. Designed with a fully contained process zone, it delivers all the dosing precision and production capability of the standard capsule filling range while incorporating robust containment features that minimise exposure risk throughout the capsule feeding, filling, and discharge stages. Built to meet ATEX, CE, GAMP5, and cGMP compliance requirements, the Containment Series supports high-containment pharmaceutical manufacturing without compromising fill accuracy or operational efficiency.
Liquid Filler & Band Sealer
The F Plus Liquid Filler & Band Sealer is a specialised encapsulation system designed for filling two-piece hard capsules with liquid, semi-solid, or paste formulations extending the range of capsule-based drug delivery beyond conventional powder and granule applications. Featuring a precision liquid dosing system with no-fill-no-capsule detection and a integrated band sealing unit that applies a tamper-evident gelatin seal around each filled capsule, it ensures both dosing accuracy and capsule integrity throughout the production process. Ideal for formulations such as oils, suspensions, hot-melts, and lipid-based drug delivery systems, it is built for pharmaceutical and nutraceutical manufacturers requiring a reliable, contained, and cGMP-compliant liquid encapsulation solution.
Ancillaries
The F Plus Encapsulation Ancillaries are a range of complementary equipment designed to support, enhance, and complete the capsule filling production line. From empty capsule sorting and de-dusting to capsule polishing, checkweighing, and metal detection, each ancillary unit integrates seamlessly with the F Plus capsule filling range to ensure product quality, process efficiency, and regulatory compliance at every stage of production. Whether configuring a new encapsulation line or upgrading an existing one, F Plus ancillaries provide the additional capabilities needed to deliver finished capsules that consistently meet cGMP, pharmacopeial, and quality standards.
Planning your capsule filling line?
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Frequently Asked Questions
Questions before you begin?
Start with the essentials, then speak with our team about your formulation, capacity and facility requirements.
It separates empty hard capsules, doses the formulation into the capsule body, rejoins the cap and body, and ejects the finished capsule with controlled fill weight and minimal manual handling.
Depending on the configuration, the machines can fill powders, granules, pellets, tablets, micro-tablets, combinations, and specialised liquid or semi-solid formulations.
A semi automatic capsule filling machine combines operator-assisted loading with automated dosing and closing. A fully automatic system integrates capsule handling and dosing for higher throughput and lower routine intervention.
Yes. The XTR Series is designed for high-throughput commercial encapsulation with advanced dosing, process monitoring, compliant controls, and changeover features intended to support production uptime.
Yes. Containment configurations can reduce operator and environmental exposure during capsule feeding, dosing, filling, and discharge for potent or sensitising APIs.
Yes. The Liquid Filler & Band Sealer is designed for two-piece hard capsules filled with liquid, semi-solid, or paste formulations, including oils, suspensions, and lipid-based delivery systems, with integrated band sealing for tamper-evident closure.
